【Product Introduction】
●Reduces fever and alleviates pain caused by ibuprofen, such as sore throat and fever.
●Pseudoephedrine hydrochloride suppresses nasal mucous membrane congestion and relieves nasal stuffiness.
●Five ingredients work in a balanced manner to relieve various cold symptoms.
●Small, easy-to-swallow white capsule-type tablets.
●Precautions for Use
■■ Things you must not do ■■
(Disregarding these may worsen current symptoms or increase the risk of side effects or accidents)
1. Do not take if you are:
(1) Have had allergic reactions to this medication or its ingredients.
(2) Have experienced asthma after taking this or other cold or fever-reducing/pain-relieving medicines.
(3) Under 15 years old.
(4) Pregnant within 12 weeks of expected delivery.
(5) Have symptoms such as difficulty urinating due to prostate enlargement.
(6) Diagnosed with hypertension, heart disease, thyroid dysfunction, or diabetes.
2. Do not use other medications, including other cold medicines, fever reducers, pain relievers, sedatives, cough suppressants with expectorants, antihistamines (such as nasal allergy medicines, motion sickness medicines, allergy medicines, hypnotics, etc.) while taking this medication.
3. Do not operate vehicles or machinery after taking this medication.
( drowsiness may occur.)
4. Do not take if breastfeeding, or avoid breastfeeding if taking this medication.
5. Do not drink alcohol before or after taking.
6. Do not take for more than 5 days.
■■ Consult before use ■■
1. Consult a doctor or pharmacist before taking if you are:
(1) Undergoing treatment by a doctor or dentist.
(2) Pregnant or suspected to be pregnant.
(3) Elderly.
(4) Have experienced allergic reactions to medicines.
(5) Have symptoms such as high fever or difficulty urinating.
(6) Diagnosed with liver disease, kidney disease, glaucoma, systemic lupus erythematosus, or mixed connective tissue disease.
(7) Have had stomach or duodenal ulcers, ulcerative colitis, or Crohn’s disease.
(8) Under treatment with monoamine oxidase inhibitors (such as selegiline).
(9) Have experienced insomnia, dizziness, weakness, shivering, palpitations after taking cold medicines, cough suppressants, nasal allergy medicines, etc.
2. If any of the following symptoms appear after taking, stop immediately and consult a doctor or pharmacist with this document, as side effects may be occurring:
[Related Parts] [Symptoms]
Skin: Rash, redness, itching, bruising
Digestive system: Nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, indigestion, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stools
Nervous system: Dizziness, insomnia, nervousness, seizures
Circulatory system: Palpitations
Respiratory system: Shortness of breath
Urinary system: Difficulty urinating
Others: Swelling, facial flushing, hot flashes, blurred vision, tinnitus, nosebleeds, gum bleeding, bleeding that is hard to stop, bleeding, back pain, excessive lowering of body temperature, fatigue
Rarely, severe symptoms listed below may occur. Seek immediate medical attention if they do.
[Serious Symptoms] Shock (Anaphylaxis)
[Symptoms] Immediately after taking, may appear as skin itching, hives, hoarseness, sneezing, throat itching, breathing difficulty, palpitations, altered consciousness, etc.
[Serious Symptoms] Stevens-Johnson syndrome, toxic epidermal necrolysis
[Symptoms] High fever, eye redness, eye discharge, lip sores, sore throat, widespread skin rash and redness, which may persist or worsen rapidly.
[Serious Symptoms] Liver dysfunction
[Symptoms] Fever, itching, rash, jaundice (yellowing of skin and eyes), dark urine, general fatigue, loss of appetite.
[Serious Symptoms] Kidney impairment
[Symptoms] Fever, rash, decreased urine output, swelling, fatigue, joint pain, diarrhea.
[Serious Symptoms] Interstitial pneumonia
[Symptoms] Shortness of breath or difficulty breathing on exertion, cough, fever, which may occur suddenly or persist.
[Serious Symptoms] Asthma
[Symptoms] Wheezing, whistling sounds when breathing, difficulty breathing.
[Serious Symptoms] Aseptic meningitis
[Symptoms] Severe headache with neck stiffness, fever, nausea, vomiting, especially reported in patients undergoing treatment for systemic lupus erythematosus or mixed connective tissue disease.
[Serious Symptoms] Aplastic anemia
[Symptoms] Bruising, nosebleeds, gum bleeding, fever, pallor, fatigue, palpitations, shortness of breath, feeling faint, hematuria.
[Serious Symptoms] Agranulocytosis
[Symptoms] Sudden high fever, chills, sore throat.
3. If any of the following symptoms appear after taking, discontinue immediately and consult a doctor or pharmacist with this document, as symptoms may worsen or persist:
- Constipation, dry mouth, drowsiness.
4. If symptoms do not improve after 5-6 doses (especially if fever continues for more than 3 days or recurs), stop taking and consult a healthcare professional.
●Efficacy and Indications
Relief of various cold symptoms (sore throat, fever, nasal congestion, runny nose, chills, headache, joint pain, muscle pain, cough, sneezing).
●Usage and Dosage
Take the following amount within 30 minutes after meals with water or warm water, without chewing.
〔Age〕 15 years and older
〔Per Dose〕 2 tablets
〔Frequency〕 3 times a day
〔Age〕 Under 15 years
〔Per Dose〕 Do not take
〔Frequency〕 Do not take
(Precautions related to usage and dosage)
(1) Follow the prescribed usage and dosage strictly.
(2) How to remove capsules (tablets):
Press the protruding part of the blister pack firmly with your fingertip to tear the aluminum foil on the back, then take out and swallow.
(Accidentally swallowing whole or improper removal may cause injury to the esophageal mucosa or other accidents.)
●Ingredients and Amounts
In 6 tablets (daily dose):
[Ingredients] Ibuprofen
[Content] 450 mg
[Function] Reduces fever and alleviates pain.
[Ingredients] Pseudoephedrine hydrochloride
[Content] 135 mg
[Function] Relieves nasal congestion and runny nose.
[Ingredients] Chlorpheniramine maleate
[Content] 7.5 mg
[Function] Relieves runny nose and sneezing.
[Ingredients] Dextromethorphan hydrobromide
[Content] 24 mg
[Function] Suppresses cough.
[Ingredients] Caffeine anhydrous
[Content] 75 mg
[Function] Relieves headache.
Additives: Lactose monohydrate, Crosscarmellose Na, Hydroxypropyl cellulose, Cellulose, Magnesium stearate, Hypromellose, Titanium dioxide, Corn starch
●Storage and Handling Precautions
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (to prevent misuse or changes in quality).
(4) Do not take products past their expiration date.
(5) Write the date of opening on the "Open Date" column on the box when opening the inner bag (aluminum foil).
(6) Once opened, consume within approximately 6 months for quality preservation.
●Contact Information
For inquiries about this product, please contact the store where purchased or the following:
Takeda Pharmaceutical Company Healthcare Division "Customer Consultation Office"
〒103-8668 Tokyo, Chuo-ku, Nihonbashi 2-12-10
0120-567087
9:00–17:00 (excluding Saturdays, Sundays, and holidays)
●Takeda Health Site Manufacturer and Distributor
Takeda Pharmaceutical Company
〒540-8645 Osaka, Chuo-ku, Doshomachi 4-1-1
Package may be changed without notice. Thank you for your understanding.
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