Lion Bufferin Premium [40 tablets]

【Expiration Date of Medicine】
We sell products with an expiration date of more than 180 days.

【Features】＜Antipyretic Analgesic＞
Bufferin has products with different active ingredients. The antipyretic and analgesic ingredients in this product are ibuprofen and acetaminophen. When consulting a doctor, dentist, or pharmacist, please inform them of ibuprofen and acetaminophen.

BUFFERIN Premium Formula – 4 Features
- Pain relief ingredients effective for headaches and menstrual pain
- Ingredients that protect the stomach
- Quick Attack Tablets※
- Easy-to-swallow small tablets
※Bufferin’s unique technology combining rapid disintegration of the tablet and rapid dissolution of ibuprofen
【Precautions for Use】■■ Do Not Do ■■
(Not following these may worsen current symptoms or increase the risk of side effects or accidents)
1. Do not take if you:
(1) Have had allergic reactions to this product or its ingredients.
(2) Have experienced asthma caused by this product or other antipyretic analgesics or cold medicines.
(3) Are under 15 years old.
(4) Are pregnant within 12 weeks before the expected delivery date.
2. Do not take any of the following medicines while using this product:
Other antipyretic analgesics, cold medicines, sedatives, motion sickness medicines.
3. Do not drive vehicles or operate machinery after taking this medicine.
(Drowsiness or other symptoms may occur.)
4. Do not drink alcohol before or after taking this medicine.
5. Do not take continuously for a long time.
■■ Consult a Doctor or Pharmacist ■■
1. Before taking, consult a doctor, dentist, or pharmacist if you:
(1) Are receiving treatment from a doctor or dentist.
(2) Are pregnant or think you may be pregnant.
(3) Are breastfeeding.
(4) Are elderly.
(5) Have had allergic reactions to medicines.
(6) Have been diagnosed with any of the following:
Heart disease, kidney disease, liver disease, systemic lupus erythematosus, mixed connective tissue disease.
(7) Have a history of the following diseases:
Stomach or duodenal ulcer, ulcerative colitis, Crohn’s disease.
2. Stop taking and consult a doctor, dentist, or pharmacist immediately if you experience any of the following symptoms after taking as they may be side effects:

Affected Area: Skin
Symptoms: Rash, redness, itching, bruising

Affected Area: Digestive System
Symptoms: Nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, mouth ulcers, heartburn, indigestion, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stool

Affected Area: Nervous System
Symptom: Dizziness

Affected Area: Circulatory System
Symptom: Palpitations

Affected Area: Respiratory System
Symptom: Shortness of breath

Affected Area: Others
Symptoms: Blurred vision, tinnitus, swelling, nosebleed, bleeding gums, prolonged bleeding, bleeding, back pain, excessive body temperature drop, fatigue

Rare but serious symptoms may occur. In such cases, seek medical attention immediately.

Condition: Shock (Anaphylaxis)
Symptoms: Immediately after taking, itching of the skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, loss of consciousness, etc.

Condition: Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, Acute Generalized Exanthematous Pustulosis
Symptoms: High fever, eye redness, eye discharge, lip erosion, sore throat, widespread skin rash/redness, small blisters (pustules) on reddened skin, general fatigue, loss of appetite, persistent or rapidly worsening symptoms.

Condition: Drug Hypersensitivity Syndrome
Symptoms: Widespread skin redness, systemic rash, fever, fatigue, swollen lymph nodes (neck, armpits, groin), etc.

Condition: Liver Dysfunction
Symptoms: Fever, itching, rash, jaundice (yellowing of skin and whites of eyes), dark urine, general fatigue, loss of appetite, etc.

Condition: Kidney Disorder
Symptoms: Fever, rash, decreased urine output, swelling, fatigue, joint pain, diarrhea, etc.

Condition: Aseptic Meningitis
Symptoms: Severe headache with neck stiffness, fever, nausea, vomiting, etc.
(This is frequently reported in patients treated for systemic lupus erythematosus or mixed connective tissue disease.)

Condition: Myocardial Infarction
Symptoms: Tight chest pain, difficulty breathing, cold sweat.

Condition: Cerebrovascular Disorder
Symptoms: Sudden decreased or loss of consciousness, difficulty moving one side of the body, headache, vomiting, dizziness, difficulty speaking or finding words.

Condition: Interstitial Pneumonia
Symptoms: Shortness of breath or difficulty breathing after climbing stairs or slight exertion, dry cough, fever, sudden onset or persistence.

Condition: Asthma
Symptoms: Wheezing or whistling while breathing, difficulty breathing.

Condition: Aplastic Anemia
Symptoms: Bruising, nosebleeds, bleeding gums, fever, pale skin or mucous membranes, fatigue, palpitations, shortness of breath, dizziness, blood in urine.

Condition: Agranulocytosis
Symptoms: Sudden high fever, chills, sore throat.

3. After taking, if you experience constipation or drowsiness and these symptoms persist or worsen, stop taking and consult a doctor, pharmacist, or dentist with this document.

4. If symptoms do not improve after 5 to 6 doses, stop taking and consult a doctor, dentist, or pharmacist with this document.
【Indications】
(1) Pain relief for headache, menstrual pain, stiff shoulders, lower back pain, joint pain, neuralgia, muscle pain, sore throat, toothache, pain after tooth extraction, bruises, sprains, fractures, trauma, ear pain.
(2) Fever reduction during chills or fever.
【Dosage and Administration】
Avoid taking on an empty stomach as much as possible. Take at intervals of 4 hours or more.
Take the following amounts with water or lukewarm water.

Age: Adults (15 years and older)
Dose: 2 tablets per dose
Maximum frequency: 3 times a day

Age: Under 15 years old
Do not take


(1) Strictly follow the dosage and administration instructions.
(2) How to remove tablets
Press firmly on the raised part of the PTP sheet with your fingertip to break the aluminum foil on the back and take out the tablet before swallowing. (Swallowing it directly may cause injury to the esophageal mucosa.)
【Ingredients and Amounts】(per 2 tablets)
Active Ingredient: Ibuprofen
Amount: 130 mg
Action: Relieves pain and reduces fever.

Active Ingredient: Acetaminophen
Amount: 130 mg
Action: Relieves pain and reduces fever.

Active Ingredient: Anhydrous Caffeine
Amount: 80 mg
Action: Assists pain relief and alleviates headache.

Active Ingredient: Allylisopropylacetylurea
Amount: 60 mg
Action: Assists pain relief and alleviates headache.

Active Ingredient: Dried Aluminum Hydroxide Gel
Amount: 70 mg
Action: Protects the stomach lining and prevents stomach irritation.

Additives include cellulose, hydroxypropyl cellulose, lactic acid, D-mannitol, potassium dihydrogen phosphate, silicon dioxide, magnesium stearate, partially saponified polyvinyl alcohol, talc, titanium oxide, glycerin fatty acid ester, sodium lauryl sulfate.
【Storage and Handling Precautions】
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers.
(This may cause misuse or quality changes.)
(4) Do not use products past their expiration date.
(5) To avoid deterioration, do not damage the aluminum foil backing of tablets you do not take.
【Contact Information】
Lion Corporation Customer Center 0120-813-752
Reception hours: 9:00–17:00 (excluding Saturdays, Sundays, and holidays)

Lion Corporation
1-3-28 Kuramae, Taito-ku, Tokyo 111-8644

※ Packaging design and others may change without notice. Thank you for your understanding.