Product Introduction
● Due to the antipyretic and analgesic effects of ibuprofen, it alleviates fever, chills (rigors), headache, sore throat, and joint pain caused by colds.
● Six ingredients work in a balanced manner to relieve various symptoms of colds.
● Contains hesperidin, a type of vitamin P found in citrus fruits.
● Easy-to-swallow small, white to pale yellow circular tablets.
Regarding the Sale of Pharmaceuticals
● Precautions for Use
■■ Things Not to Do ■■
(Not following these may worsen current symptoms or increase the risk of side effects or accidents)
1. Do not take if you fall under any of the following:
(1) Those who have had allergic reactions to this product or its ingredients.
(2) Those who have experienced asthma triggered by this product or other cold or antipyretic analgesic medicines.
(3) Children under 15 years old.
(4) Pregnant women within 12 weeks of the expected delivery date.
2. While taking this product, do not use any of the following medications:
Other cold medicines, antipyretic analgesics, sedatives, cough expectorants, antihistamine-containing oral medicines (such as oral medicines for rhinitis, motion sickness, allergies, hypnotics, and sedatives).
3. Do not drive vehicles or operate machinery after taking this product
(Drowsiness or similar symptoms may occur).
4. Nursing mothers should avoid taking this product, or avoid breastfeeding if taking it.
5. Do not consume alcohol before or after taking the medicine.
6. Do not take for more than 5 days.
■■ Consult a Doctor or Pharmacist ■■
1. Consult a doctor, dentist, or pharmacist before taking if you fall under any of the following:
(1) Those receiving medical or dental treatment.
(2) Pregnant or possibly pregnant women.
(3) Elderly people.
(4) Those who have had allergic reactions to drugs or other substances.
(5) Those with the following symptoms:
High fever, difficulty urinating.
(6) Those diagnosed with the following:
Thyroid dysfunction, diabetes, heart disease, hypertension, liver disease, kidney disease, glaucoma,
systemic lupus erythematosus, mixed connective tissue disease, respiratory dysfunction,
obstructive sleep apnea syndrome, obesity.
(7) Those with a history of the following diseases:
Gastric or duodenal ulcer, ulcerative colitis, Crohn's disease.
2. If the following symptoms appear after taking the medicine, they may be side effects; stop taking it immediately and consult a doctor or pharmacist with this document.
Affected Area … Symptoms
Skin … Rash, redness, itching, bruising
Digestive system … Nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn,
indigestion, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stools
Central nervous system … Dizziness
Circulatory system … Palpitations
Respiratory system … Shortness of breath
Urinary system … Difficulty urinating
Others … Blurred vision, tinnitus, swelling, nosebleeds, bleeding gums, easy bleeding, bleeding, back pain, excessive lowering of body temperature, fatigue
Rare but serious symptoms may occur.
If so, seek medical attention immediately.
Symptom Name … Symptoms
Shock (Anaphylaxis) … Immediately after taking, itching of the skin, hives, hoarseness, sneezing, throat itching, difficulty breathing, palpitations, confusion.
Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis … High fever, eye redness, eye discharge, lip erosion, sore throat,
widespread rash/redness of the skin that persists or rapidly worsens.
Liver dysfunction … Fever, itching, rash, jaundice (yellowing of skin or whites of eyes), dark urine,
general fatigue, loss of appetite.
Kidney disorder … Fever, rash, decreased urine output, generalized swelling, fatigue, joint pain,
diarrhea.
Aseptic meningitis … Severe headache with neck stiffness, fever, nausea, vomiting
(often reported in patients treated for systemic lupus erythematosus or mixed connective tissue disease).
Interstitial pneumonia … Shortness of breath or difficulty breathing on climbing stairs or slight exertion, dry cough, fever, which may appear suddenly or persist.
Asthma … Wheezing or whistling while breathing, difficulty breathing.
Aplastic anemia … Bruising, nosebleeds, bleeding gums, fever, pale skin or mucous membranes, fatigue, palpitations, shortness of breath, dizziness, blood in urine.
Agranulocytosis … Sudden high fever, chills, sore throat.
Respiratory depression … Shortness of breath, difficulty breathing.
3. The following symptoms may appear after taking the medicine; if these symptoms persist or worsen, stop taking and consult a doctor, pharmacist, or registered distributor with this document:
Constipation, dry mouth, drowsiness.
4. If symptoms do not improve after 5–6 doses (especially if fever lasts more than 3 days or recurs), stop taking and consult a doctor or pharmacist with this document.
● Indications and Effects
Relief of various cold symptoms (fever, chills, headache, sore throat, joint pain, runny nose, nasal congestion,
muscle pain, cough, phlegm, sneezing).
● Dosage and Administration
Take the following amount within about 30 minutes after meals with water or hot water without chewing.
Age … Single dose … Number of doses per day
15 years and older … 2 tablets … 3 times
Under 15 years … Do not take
● Ingredients and Quantities
Per 6 tablets (daily dose)
Ingredient … Amount … Action
Ibuprofen … 450 mg … Reduces fever and relieves pain
Chlorpheniramine maleate … 7.5 mg … Relieves runny nose and sneezing
dl-Methylephedrine hydrochloride … 60 mg … Relieves cough and phlegm
Dihydrocodeine phosphate … 24 mg … Relieves cough
Anhydrous caffeine … 75 mg … Relieves headache
Hesperidin … 90 mg … Vitamin-like substance (a type of vitamin P)
Additives: Lactose hydrate, croscarmellose sodium, hypromellose,
hydroxypropyl cellulose, cellulose, magnesium stearate, titanium dioxide,
carnauba wax, purified beeswax, corn starch
● Storage and Handling Precautions
(1) Store in the box in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (may cause misuse or quality changes).
(4) Do not use after the expiration date.
(5) Write the date of opening the inner bag (aluminum bag) in the "Opening Date" field on the box.
(6) After opening the inner bag (aluminum bag), for quality preservation, consume within 6 months as a guideline.
● Contact Information
For inquiries about this product, please contact the store where you purchased it or the following:
Takeda Consumer Healthcare Co., Ltd. "Customer Consultation Room"
1-1, Doshomachi 4-chome, Chuo-ku, Osaka 541-0045, Japan
0120-567-087
9:00–17:00 (excluding Saturdays, Sundays, and holidays)
Takeda Health Website
Package design may change without notice.
Thank you for your understanding.
Phone: