KAIKEN Pack IB Granules [9 packets]

【Expiration Date of Medicines】
Products with an expiration date of more than 180 days are sold.

Kaigen Pack IB Granules

Suppresses the production of pain-causing substances (prostaglandins).
This is an antipyretic and analgesic powder containing herbal ingredients and ibuprofen.

■Precautions for Use
・Things you must not do
(If not followed, current symptoms may worsen, or side effects and accidents may become more likely)

1. Do not take if you are:
（1）Someone who has had allergic reactions to this medication or its components.
（2）Someone who has experienced asthma after taking this or other antipyretic/analgesic or cold medicines.
（3）Children under 15 years old.
（4）Pregnant women within 12 weeks of expected delivery.

2. While taking this medication, do not take
Other antipyretic/analgesics, cold medicines, sedatives.

3. Do not consume alcohol before or after taking.

4. Do not use for long-term continuous use.

・Consultation required
1. Before taking, consult a doctor, dentist, pharmacist, or similar if you are:
（1）Under medical or dental treatment.
（2）Pregnant or suspected of being pregnant.
（3）Breastfeeding.
（4）Elderly.
（5）Have had allergic reactions to medicines or other substances.
（6）Diagnosed with:
　Heart disease, kidney disease, liver disease, systemic lupus erythematosus, mixed connective tissue disease.
（7）Have had:
　Gastric or duodenal ulcers, ulcerative colitis, Crohn’s disease.

2. If symptoms such as the following appear after taking, stop immediately and consult a doctor, dentist, pharmacist, or similar with this instruction sheet, as side effects may occur:

Related areas: Symptoms
Skin: Rash, redness, itching, bruising
Digestive system: Nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, indigestion, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stool
Neuropsychiatric: Dizziness
Circulatory: Palpitations
Respiratory: Shortness of breath
Others: Blurred vision, tinnitus, swelling, nosebleed, gum bleeding, bleeding that is hard to stop, bleeding, back pain, excessive hypothermia, fatigue

Rarely, severe symptoms may occur; in such cases, seek immediate medical attention.

Symptoms: Symptoms
- Shock (Anaphylaxis): Immediate symptoms include skin itching, hives, hoarseness, sneezing, throat itching, difficulty breathing, palpitations, altered consciousness.
- Stevens-Johnson syndrome, Toxic epidermal necrolysis, Acute generalized exanthematous pustulosis: High fever, eye redness, discharge, lip sores, sore throat, widespread skin rash and redness, small pustules on reddened skin, fatigue, loss of appetite, worsening or rapid onset.
- Liver dysfunction: Fever, itching, rash, jaundice (yellowing of skin and eyes), dark urine, general fatigue, loss of appetite.
- Kidney impairment: Fever, rash, decreased urine output, swelling, fatigue, joint pain, diarrhea.
- Sterile meningitis: Severe headache with neck stiffness, fever, nausea, vomiting (noted especially in patients treated for systemic lupus erythematosus or mixed connective tissue disease).
- Asthma: Wheezing, shortness of breath, etc.
- Aplastic anemia: Bruising, nosebleeds, gum bleeding, fever, pallor, fatigue, palpitations, shortness of breath, dizziness, hematuria.
- Agranulocytosis: Sudden high fever, chills, sore throat.

3. After taking, symptoms such as the following may appear. If symptoms persist or worsen, stop taking and consult a healthcare professional with this sheet:
Constipation

4. If after 5-6 doses, symptoms do not improve, stop taking and consult a healthcare professional with this sheet.

■Indications & Effects
- Menstrual pain (dysmenorrhea), headache, toothache, post-extraction pain, sore throat, earache, joint pain, neuralgia, back pain, muscle pain, shoulder stiffness, bruises, fractures, sprains, trauma pain.
- Relief of fever and chills.

■Usage & Dosage
Take the following amount, preferably not on an empty stomach. Maintain an interval of at least 4 hours between doses.

Age: Single dose: Number of doses per day
・15 years and older：1 packet: up to 3 times
・Under 15 years：Do not take

＜Notes on Usage & Dosage＞
- Strictly adhere to the prescribed amount and frequency.

■Ingredients & Amounts
In 3 packets (4.2g), containing:

Ingredient: Amount: Function
Ibuprofen: 450mg: Suppresses excessive production of prostaglandins, relieving pain.
Caffeine anhydrous: 240mg: Enhances the pain-relief effect of other ingredients, alleviates headache.
Licorice extract: 300mg: Relieves muscle spasms and relaxes muscles.
Peony extract: 125mg (equivalent to 500mg of peony): Regulates muscle tension and relaxation, easing pain.

Additives include D-mannitol, lactose monohydrate, carmellose, light anhydrous silicic acid, L-menthol, hydroxypropyl cellulose.

■Storage & Handling Precautions
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (may cause misuse or deterioration).
(4) Do not take products past the expiration date printed on the outer box.

【Country of Origin】
Japan

【Inquiries】
Company: Kaigen Pharma Co., Ltd. "Customer Service"
Phone: 06-6202-8911
Hours: 9:00–17:00 (excluding weekends and holidays)

【Manufactured & Sold By】
Kaigen Pharma Co., Ltd.
Address: 2-5-14 Doshomachi, Chuo-ku, Osaka City

【Product Category】
"Class (2) OTC drug"

※Package design and other details are subject to change without notice. Thank you for your understanding.