Coragen IB Tablets TXα [45 tablets]

【Expiration date of medicines】
Products with an expiration period of more than 180 days are being sold.

This is a comprehensive cold medicine containing 600mg of the antipyretic and analgesic ingredient "Ibuprofen" (daily dose).

It effectively relieves symptoms of severe sore throat cold or intense fever cold.

By taking this medication, the seven active ingredients that exhibit excellent effects, such as the anti-inflammatory component "Tranexamic Acid" and the expectorant "Ambroxol Hydrochloride," work synergistically to alleviate the symptoms of the severe cold, making you feel better.

■ Precautions for use
・Things you must not do
(If not followed, current symptoms may worsen, and side effects or accidents are more likely to occur)

1. Do not take this if you are
(1) Someone who has had allergic reactions to this medicine or its ingredients.
(2) Someone who has experienced asthma after taking this or other cold medicines, antipyretics, or analgesics.
(3) Children under 15 years old.
(4) Someone undergoing treatment at a medical facility for conditions such as stomach or duodenal ulcers, blood disorders, liver disease, kidney disease, heart disease, high blood pressure, or receiving Zidovudine (Retrovir).
(5) Pregnant women within 12 weeks of expected delivery.

2. Do not use any other medicines, including
- Other cold medicines, antipyretics, analgesics, sedatives, cough and expectorant medicines, antihistamines (such as for rhinitis, motion sickness, allergy medications), or oral tranexamic acid, while taking this medication.

3. Do not operate vehicles or machinery after taking this medication
(sleepiness and other effects may occur).

4. Nursing women should either not take this medication or avoid breastfeeding if they do.

5. Do not drink alcohol before or after taking this medication.

6. Do not take for more than 5 days.

■ When to consult a doctor
1. Before taking, consult a doctor, pharmacist, or medical professional if you are
(1) Under medical or dental treatment.
(2) Pregnant or suspected to be pregnant.
(3) Elderly.
(4) Have experienced allergic reactions to medications or substances.
(5) Have symptoms such as high fever or difficulty urinating.
(6) Diagnosed with conditions such as hyperthyroidism, diabetes, glaucoma, systemic lupus erythematosus, mixed connective tissue disease, thrombosis (stroke, myocardial infarction, venous thrombosis), risks of thrombosis, asthma, respiratory dysfunction, obstructive sleep apnea syndrome, or obesity.
(7) Have had illnesses like stomach/duodenal ulcers, ulcerative colitis, Crohn’s disease, blood disorders, liver or kidney diseases.

2. If any of the following symptoms appear after taking the medicine, discontinue immediately and consult a doctor, pharmacist, or medical professional with this leaflet, as these may be side effects:
- Skin: rash, redness, itching
- Digestive system: nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, mouth ulcers, heartburn, indigestion, gastrointestinal bleeding, abdominal pain, diarrhea, bloating
- Nervous system: dizziness, insomnia, depression
- Circulatory: palpitations
- Respiratory: shortness of breath
- Urinary: difficulty urinating
- Others: blurred vision, tinnitus, swelling, back pain, numbness

*Rarely, severe symptoms such as the following may occur. Seek medical attention immediately if they do:*
- Shock (anaphylaxis): Symptoms include itching, hives, hoarseness, sneezing, throat itching, difficulty breathing, palpitations, confusion occurring immediately after use.
- Stevens-Johnson Syndrome, toxic epidermal necrolysis, or acute generalized exanthematous pustulosis: high fever, eye redness, eye discharge, lip sores, sore throat, extensive rash/redness, small blisters on red skin, fatigue, loss of appetite, which may worsen rapidly.
- Liver dysfunction: fever, itching, rash, jaundice (yellowing of skin or eyes), dark urine, fatigue, loss of appetite.
- Kidney impairment: fever, rash, decreased urine output, swelling, fatigue, joint pain, diarrhea.
- Interstitial pneumonia: shortness of breath, cough, fever that appears suddenly or persists, especially after exertion.
- Aseptic meningitis: severe headache with neck stiffness, fever, nausea, vomiting (more common in patients treated for systemic lupus erythematosus or mixed connective tissue disease).
- Asthma: wheezing, whistling sounds, difficulty breathing.
- Blood disorders: sore throat, fever, general fatigue, pale face or eyelids, bleeding tendencies (gum bleeding, nosebleeds), bruising that does not fade when pressed.
- Digestive issues: dark stools, vomiting blood, bloody stools, mucus/blood mixed diarrhea.
- Respiratory depression: shortness of breath, difficulty breathing.

3. If symptoms such as excessive body temperature decrease, collapse (weakness), cold limbs occur, stop taking immediately and consult a doctor, pharmacist, or medical professional with this leaflet.

4. If symptoms such as persistent nausea, dry mouth, or drowsiness occur, stop taking the medicine and consult a healthcare professional.

5. If symptoms do not improve after 5-6 doses (especially if fever lasts more than 3 days or recurs), discontinue and consult a doctor or pharmacist.

■ Efficacy and effects
Relief of cold symptoms (sore throat, fever, chills, headache, cough, phlegm, nasal discharge, nasal congestion, sneezing, joint pain, muscle pain).

■ Usage and dosage
Take the following amount with water or warm water within about 30 minutes after meals.

Age: Dose per administration: Frequency per day
- Adults (15 years and older): 3 tablets, 3 times a day
- Children under 15: Do not take

Precautions related to usage and dosage
1. Follow the instructions strictly.
2. How to take tablets
Press firmly on the convex part of the PTP sheet to break the aluminum foil on the back, then remove and take the tablet. (Swallowing the sheet directly can cause accidental injury to the esophageal mucosa.)

■ Ingredients and amounts
Ingredients: amount (per 9 tablets)
- Ibuprofen: 600mg
- Tranexamic acid: 750mg
- Ambroxol Hydrochloride: 45mg
- D-Chlorpheniramine Maleate: 3.5mg
- Dihydrocodeine Phosphate: 24mg
- D-Phenylephrine Hydrochloride: 60mg
- Caffeine Anhydrous: 75mg

Additives: anhydrous silica, hypromellose, citric acid, lactose, calcium silicate, hydroxypropyl cellulose, carmellose calcium, magnesium stearate, triacitin, talc, titanium dioxide, Yellow No. 5, carnauba wax.

■ Storage and handling precautions
(1) Store in a cool, dry place away from direct sunlight and high temperatures.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (to prevent misuse or quality deterioration).
(4) Be careful during storage and transport not to tear the aluminum foil or damage the tablets.
(5) Do not use products past the expiration date (printed on the box).

【Country of Origin】
Japan

【Inquiry】
Company: Kowa Co., Ltd. Pharmaceutical Business Division Customer Consultation Center
Phone: 03-3279-7755
Hours: Monday to Friday (excluding holidays) 9:00-17:00

【Manufacturer and Distributor】
Company: Kowa Co., Ltd.
Address: 3-4-14 Nihonbashi Honcho, Chuo-ku, Tokyo

【Product Category】
"Class 2 Over-the-Counter Drug"

※Package designs are subject to change without notice. Thank you for your understanding.